The leaves are wide with white blotches or veins. Its resources include publications (such as Dietary Supplements: What You Need To Know) and fact sheets on a variety of specific supplement ingredients and products (such as vitamin D and multivitamin/mineral supplements). The Clearinghouse does not provide medical advice, treatment recommendations, or referrals to practitioners. There is no standard dose of milk thistle, so it is best to read the dosage suggested on the packaging. Who should not take Milk Thistle Capsule? Dietary supplements are not regulated like drugs in the United States, meaning the Food and Drug Administration (FDA) does not approve them for safety and effectiveness before products are marketed. It may not be safe for people with hormone-sensitive breast cancer. Consult your doctor for more information if you have either of these serious conditions.Some herbal/dietary supplement products have been found to contain possibly harmful impurities/additives. Milk thistle is an herbal remedy derived from the milk thistle plant, also known as Silybum marianum. This is not a complete list of side effects and others may occur. Milk thistle: effects on liver disease and cirrhosis and clinical adverse effects: summary. Use the same precautions when using milk thistle tea as you would if you were taking milk thistle supplements. NCCIH has provided this material for your information. Can Apoaequorin Really Improve Your Memory? Certain people should take precautions when using milk thistle, and others may need to avoid it altogether. Keep in mind, though, that it is unknown if milk thistle tea provides the same suggested benefits as milk thistle supplements. Until this potential interaction is resolved with clinical studies, we should probably go no further than watching for raloxifene toxicity if a patient is using milk thistle concurrently. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. However, if you develop an allergic reaction after taking milk thistle, stop use and consult your doctor. Allergic reactions, abdominal problems, and estrogen and drug interactions are some of the common side effects seen in people who take this herb for extended durations. Common Names:milk thistle, Mary thistle, holy thistle, Latin Names:Silybum marianum, synonym Carduus marianus. The medical community needs more evidence to prove that milk thistle benefits human livers in the same way. Call your doctor for medical advice about side effects. These combination supplements may list health claims on the label. Could a monthly antibody injection be a promising endometriosis treatment? The following conditions are contraindicated with this drug. We avoid using tertiary references. Content is best viewed in IE9 or above, Firefox and Google Chrome browser. One study questioned the benefits of milk thistle for liver diseases. All rights reserved. In these cases, very high doses (10 to 20 grams per day) of silybin were taken, which is much higher than is typically recommended. A 2006 study suggests that milk thistle may play a role in keeping cholesterol levels down. Milk thistle is found throughout the eastern United States, California, South America, Africa, Australia, and Asia. Liquid forms of this product may contain sugar and/or alcohol. Some people also call it Mary thistle and holy thistle. A small number of studies have suggested that milk thistle extract might be beneficial for diabetes, but the conclusions about its effectiveness are not definite. Ebrahimpour koujan S, Gargari BP, Mobasseri M, Valizadeh H, Asghari-jafarabadi M. Effects of Silybum marianum (L.) Gaertn. More studies with human participants could allow scientists to say with certainty that milk thistle supports a persons immune system. Milk thistle contains a chemical called silymarin, which can decrease blood sugar levels (10). 3. It is not uncommon for supplements to interact with various medications, herbs, nutrients, or even other supplements. Spiny stems branch at the top and reach heights of 5 to 10 feet. On extremely rare occasions, milk thistle has caused severe allergic reactions as well as anaphylaxis, a potentially life-threatening allergic reaction. Milk thistle is a herbal product widely used in the United States and around the world. Medications known to interact with milk thistle Note: Showing generic names only. Substances in milk thistle may reduce blood sugar. It also seems to have antioxidant and anti-inflammatory effects. Milk thistle is sold as an oral capsule, tablet and liquid extract. Merlin Annie Raj, RD (Registered Dietitian), Merlin Annie Raj is a Registered Dietitian based out of Hyderabad, India. Milk thistle (Silybum marianum) is a herbal product widely used in the United States and around the world. There are no guidelines regarding a standard dose of milk thistle. 2012;308(3):274-82. doi:10.1001/jama.2012.8265. Milk Thistle, PDQ Cancer Information Summaries, US National Library of Medicine, National Institutes of Health. Take this product by mouth as directed. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. Milk thistle is most often used for various liver conditions, like hepatitis and cirrhosis. However, consult your doctor for the best advice. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. It may take one or two weeks for milk thistle to start working. This article explores potential milk thistle benefits and examines whether there is any scientific evidence to support its use. Follow all directions on the product package. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. [1] Silymarin is a standardized preparation extracted from the fruits (seeds) of milk thistle. Store milk thistle supplements in a cool, dry place. It can be consumed in supplement form or as a tea. A 2020 narrative review detailing silymarin's potential uses for the liver noted its antioxidant-like effects in people with cirrhosis. Rambaldi A, Jacobs BP, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases. Available for Android and iOS devices. Similar supplements to milk thistle include: Please talk with your healthcare provider about the best supplement for you. 2020;34(6):1446-1454. doi:10.1002/ptr.6620. A study from 2012 confirmed that milk thistle might not have true beneficial effects on hepatitis C. In the study, patients who took silymarin, an active component of milk thistle, daily for 24 weeks had no significant improvements in liver enzymes or other measures compared to those who took the placebo. Find out more. Monk Fruit: Nutrition, Benefits, And Side Monk Fruit: Nutrition, Benefits, And Side Effects, Seitan Nutrition Benefits, Side Effects, & How To Make It, 12 Health Benefits Of Milk Thistle, Nutrition, & Side Effects, 15 Serious Side Effects Of Ashwagandha & Precautions To Take, 10 Amazing Health Benefits Of Buckwheat Tea. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. The plants are native to the Mediterranean regions of Europe, North Africa, and the Middle East.One species has been introduced elsewhere, including in North America. Milk thistle could play an essential role in supporting bone health. 2014;10(1):31-35. doi:10.17925/EE.2014.10.01.31. Front Immunol. However, the evidence is conflicting. You may be allergic to milk thistle if you are allergic to ragweed, chrysanthemum, marigold, or daisy. Click here for additional information. Eighteen clinical trials of 1,088 participants were assessed. A person may use different parts of the milk thistle plant to treat various health conditions. Milk thistle comes in many forms, including tea. Milk thistle (Silybum marianum) is a herb loaded with antioxidants and is known for its anti-inflammatory properties. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Mothers who used milk thistle to boost their milk production reported unwanted weight gain along with irritability and nausea (16). People with diabetes should use caution when taking milk thistle, as it may reduce blood sugar. We know little about whether milk thistle is effective in people, as only a few well-designed clinical studies have been conducted. Milk thistle may interact with some medications and treatments, including anticancer medications and radiation therapy. Side effects are always possible when taking supplements. You can find milk thistle as loose-leaf tea or in tea bags. 2015;22(2):290-296. doi:10.1016/j.phymed.2014.12.010. This is not a complete list of side effects and others may occur. Milk thistle is thought to be safe for most people, but precautions should be taken as side effects are possible. Scientists think this creates a detoxifying effect, which is why milk thistle may be beneficial for liver problems. Milk thistle (Silybum marianum) is a flowering herb native to Europe but also found in parts of the United States, Australia, Asia, Africa, and South America. However, many of these potential benefits are not backed by science. Medical research on milk thistle and liver health has led to mixed results. Milk thistle may help strengthen a persons immune response. Milk Thistle; Silybum marianum; St. Mary's Thistle. High cholesterol can lead to problems with heart health and increase a persons chance of stroke. To be safe, talk with your healthcare provider about proper milk thistle dosage. Milk thistle had no effect on any of the drugs. Common side effects of milk thistle reported in studies include: Typically, side effects will subside once you stop using milk thistle. 1982;17:51721. You might also get the herb at your nearest supermarket/pharmacy. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. 1997-. Taking it along with estrogen pills might reduce their effectiveness. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. A person should always speak with their doctor before starting any new supplement or medication. Selected from data included with permission and copyrighted by First Databank, Inc. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. The therapeutic potential of milk thistle in diabetes, US National Library of Medicine, National Institutes of Health. 2005;100(11):2583-91. doi:10.1111/j.1572-0241.2005.00262.x. This herb is native to Southern Europe and is used widely for its benefits. 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